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Radiotherapy
All patients in Group 1 were treated with linear accelerators with 4-18 MV photons. A two-field opposed lateral technique was used in 10 patients, a three-field technique in 25 patients, a five-field technique in 14 patients, a combination of these techniques in 25 patients, and a rotation technique in 2 patients. In the time period 1985 to 1990, the radiation dose to the tumor was prescribed at the tumor encompassing isodose. From 1991 to 1998, it was prescribed at a central point in the tumor according to the recommendations of the International Commission on Radiation Units and Measurements (ICRU)16. Total radiation dose ranged from 45.0 to 55.8 Gray (Gy). The daily radiation fraction size varied from 1.8 to 2.0 Gy. The median overall treatment time was 35 days (range, 30 – 42 days). The radiation fraction schemes used were 45 Gy in 25 daily fractions (n = 44; 58%), 50 Gy in 25 daily fractions (n = 19; 25%), 50.4 Gy in 28 daily fractions (n = 7; 9%), 46 Gy in 23 daily fractions (n = 5; 7%), and 55.8 Gy in 31 daily fractions (n = 1; 1%). All radiation treatment fields were applied daily, 5 times a week.
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