Acromegaly is an uncommon disease, mostly caused by a growth hormone (GH)- secre-ting pituitary adenoma. Surgery, drug therapy with somatostatin analogs and external beam radiation therapy are currently the available treatment options8. Postoperative
radiation therapy is performed to reduce the time span of medical treatment, to norma-lize GH hypersecretion, and to prevent regrowth of residual tumour10.
In the past decades, scattered reports on radiation optic neuropathy (RON) have appeared in the literature4. RON is usually defined as a sudden and profound irrever-sible vision loss due to damage of the optic nerves or damage of the chiasm caused by radiation therapy7. The aim of this retrospective study is to describe the occurrence of RON in a cohort of patients treated with radiation therapy for a GH-secreting pituitary adenoma.